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. 2007 Jul 30;8(7):R150. doi: 10.1186/gb-2007-8-7-r150

Table 1.

Forty-two pathogens included in PHIDIAS

Pathogens (disease) CDC/NIAID category No. of genomes Phinfo Pacodom Phinet
1 Bacillus anthracis (anthrax) A/A 3 4,588
2 Brucella spp. (brucellosis) B/B 4 4,267
3 Burkholderia mallei (glanders) B/B 1 4,679
4 Burkholderia pseudomallei (Melioidosis) B/B 2 5,093
5 Campylobacter jejuni (food safety threat) /B 2 3,235
6 Clostridium botulinum (botulism) A/A 0 N/A
7 Clostridium perfringens (epsilon toxin) B/B 1 3,770
8 Coxiella burnetii (Q fever) B/B 1 3,032
9 Escherichia coli (food safety threat) B/B 6 5,440
10 Francisella tularensis (tularemia) A/A 2 3,057
11 Helicobacter spp. (gastric ulcer) 5 3,374
12 Legionella pneumophila (legionnaires' disease) 3 3,974
13 Listeria monocytogenes (food safety threat) /B 2 3,999
14 Mycobacterium tuberculosis (tuberculosis) /C 2 3,991
15 Rickettsia prowazekii (typhus fever) /C 1 2,129
16 Rickettsia rickettsii (Rocky Mountain spotted fever) /C 0 N/A
17 Salmonella enterica (food safety threat) B/B 4 5,150
18 Shigella spp. (food safety threat) B/B 5 5,211
19 Vibrio spp. (water safety threat) B/B 5 5,449
20 Yersinia pestis (plague) A/A 5 4,828
21 Crimean-Congo hemorrhagic fever virus (tickborne hemorrhagic fever) C/C 1 4
22 Eastern equine encephalitis virus (encephalitis) B/B 0 N/A
23 Foot-and-mouth disease virus (foot-and-mouth disease) 7 3
24 Guanarito virus (viral hemorrhagic fever) A/A 1 0
25 Human immunodeficiency virus (AIDS) 2 8
26 Junin virus (viral hemorrhagic fever) A/A 1 0
27 Lassa virus (viral hemorrhagic fever) A/A 1 0
28 Louping ill virus (encephalomyelitis) 1 6
29 Machupo virus (viral hemorrhagic fever) A/A 1 0
30 Marburg virus (viral hemorrhagic fever) A/A 1 N/A
31 Measles virus (measles) 1 0
32 Newcastle Disease Virus (Newcastle disease) 0 N/A
33 Powassan virus (encephalitis) 0 N/A
34 Reston ebola virus (viral hemorrhagic fever) A/A 1 1
35 Rift Valley fever virus (Rift Valley fever) /A 1 3
36 Variola virus (smallpox) A/A 2 129
37 Venezuelan equine encephalitis virus (viral encephalitis) B/B 1 8
38 Yellow fever virus (yellow fever) /C 1 5
39 Cryptosporidium parvum (cryptosporidiosis) B/B 0 N/A
40 Coccidioides immitis (meningitis) 0 N/A
41 Phakopsora pachyrhizi (soybean rust) 0 N/A
42 Plasmodium falciparum (malaria) 0 N/A
Total (42 pathogens) 77 37 75,433 27

The program includes 20 bacteria (54 genomes), 18 viruses (23 genomes), and 4 parasites. The database contains 75,433 conserved domains (7,919 unique PSSMs) and PHI network information for 27 pathogens.