Table 1.
Pathogens (disease) | CDC/NIAID category | No. of genomes | Phinfo | Pacodom | Phinet | |
1 | Bacillus anthracis (anthrax) | A/A | 3 | √ | 4,588 | √ |
2 | Brucella spp. (brucellosis) | B/B | 4 | √ | 4,267 | √ |
3 | Burkholderia mallei (glanders) | B/B | 1 | √ | 4,679 | √ |
4 | Burkholderia pseudomallei (Melioidosis) | B/B | 2 | √ | 5,093 | |
5 | Campylobacter jejuni (food safety threat) | /B | 2 | 3,235 | ||
6 | Clostridium botulinum (botulism) | A/A | 0 | √ | N/A | √ |
7 | Clostridium perfringens (epsilon toxin) | B/B | 1 | 3,770 | ||
8 | Coxiella burnetii (Q fever) | B/B | 1 | √ | 3,032 | √ |
9 | Escherichia coli (food safety threat) | B/B | 6 | √ | 5,440 | √ |
10 | Francisella tularensis (tularemia) | A/A | 2 | √ | 3,057 | √ |
11 | Helicobacter spp. (gastric ulcer) | 5 | 3,374 | |||
12 | Legionella pneumophila (legionnaires' disease) | 3 | 3,974 | |||
13 | Listeria monocytogenes (food safety threat) | /B | 2 | 3,999 | ||
14 | Mycobacterium tuberculosis (tuberculosis) | /C | 2 | √ | 3,991 | |
15 | Rickettsia prowazekii (typhus fever) | /C | 1 | √ | 2,129 | √ |
16 | Rickettsia rickettsii (Rocky Mountain spotted fever) | /C | 0 | √ | N/A | √ |
17 | Salmonella enterica (food safety threat) | B/B | 4 | √ | 5,150 | √ |
18 | Shigella spp. (food safety threat) | B/B | 5 | √ | 5,211 | √ |
19 | Vibrio spp. (water safety threat) | B/B | 5 | 5,449 | ||
20 | Yersinia pestis (plague) | A/A | 5 | √ | 4,828 | √ |
21 | Crimean-Congo hemorrhagic fever virus (tickborne hemorrhagic fever) | C/C | 1 | √ | 4 | √ |
22 | Eastern equine encephalitis virus (encephalitis) | B/B | 0 | √ | N/A | √ |
23 | Foot-and-mouth disease virus (foot-and-mouth disease) | 7 | √ | 3 | ||
24 | Guanarito virus (viral hemorrhagic fever) | A/A | 1 | √ | 0 | √ |
25 | Human immunodeficiency virus (AIDS) | 2 | √ | 8 | ||
26 | Junin virus (viral hemorrhagic fever) | A/A | 1 | √ | 0 | √ |
27 | Lassa virus (viral hemorrhagic fever) | A/A | 1 | √ | 0 | √ |
28 | Louping ill virus (encephalomyelitis) | 1 | √ | 6 | √ | |
29 | Machupo virus (viral hemorrhagic fever) | A/A | 1 | √ | 0 | √ |
30 | Marburg virus (viral hemorrhagic fever) | A/A | 1 | √ | N/A | √ |
31 | Measles virus (measles) | 1 | √ | 0 | √ | |
32 | Newcastle Disease Virus (Newcastle disease) | 0 | √ | N/A | ||
33 | Powassan virus (encephalitis) | 0 | √ | N/A | √ | |
34 | Reston ebola virus (viral hemorrhagic fever) | A/A | 1 | √ | 1 | √ |
35 | Rift Valley fever virus (Rift Valley fever) | /A | 1 | √ | 3 | √ |
36 | Variola virus (smallpox) | A/A | 2 | √ | 129 | |
37 | Venezuelan equine encephalitis virus (viral encephalitis) | B/B | 1 | √ | 8 | √ |
38 | Yellow fever virus (yellow fever) | /C | 1 | √ | 5 | √ |
39 | Cryptosporidium parvum (cryptosporidiosis) | B/B | 0 | √ | N/A | |
40 | Coccidioides immitis (meningitis) | 0 | √ | N/A | ||
41 | Phakopsora pachyrhizi (soybean rust) | 0 | √ | N/A | √ | |
42 | Plasmodium falciparum (malaria) | 0 | √ | N/A | ||
Total (42 pathogens) | 77 | 37 | 75,433 | 27 |
The program includes 20 bacteria (54 genomes), 18 viruses (23 genomes), and 4 parasites. The database contains 75,433 conserved domains (7,919 unique PSSMs) and PHI network information for 27 pathogens.