Table 1.
Echocardiographic and blood pressure measurements.
Adult | Senescent | p Value | |
---|---|---|---|
Age (months) | 7.5±0.5 | 31.8±0.4 | <0.0001 |
Heart Rate (beats per min) | 484±6 | 463±7 | 0.03 |
End Systolic Dimension (mm) | 2.45±0.06 | 2.86±0.09 | <0.001 |
End Diastolic Dimension (mm) | 3.79±0.06 | 4.15±0.08 | <0.001 |
Fractional Shortening (%) | 35±1 | 31±1 | <0.01 |
Interventricular Septal Wall Thickness (mm; diastolic) | 0.81±0.01 | 0.71±0.02 | <0.001 |
Posterior Wall Thickness (mm; diastolic) | 0.80±0.02 | 0.72±0.02 | <0.001 |
End Systolic Volume (μl) | 12.1±0.7 | 18.6±1.4 | <0.001 |
End Diastolic Volume (μl) | 38.4±1.5 | 45.8±2.4 | 0.02 |
Ejection Fraction (%) | 69±1 | 60±2 | <0.001 |
Stroke Volume (μl) | 26±1 | 27±1 | 0.15 |
Systolic Blood Pressure (mmHg) | 114±3 | 111±3 | 0.48 |
Diastolic Blood Pressure (mmHg) | 102±3 | 102±4 | 0.96 |
Data presented are AVG±SEM. Sample sizes for the echocardiographic analysis are 27 adult (14 female and 13 male) and 26 senescent (12 female and 14 male). Sample sizes for the blood pressure measurements are 12 adult (6 female and 6 male) and 12 senescent (6 female and 6 male).