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Longitudinal measurements of motor nerve conduction velocities (MNCVs) in the sciatic-tibial conducting system. Note a progressive decline in MNCV in type 1 BB/Wor-rats with duration of diabetes.This decline is significantly milder in type 2 BBZDR/Wor-rats and only become significant after 4 months of diabetes. C-peptide replacement from onset of diabetes had significant effects on MNCVs although these are not completely prevented [17, 39, 47].
