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. Author manuscript; available in PMC: 2008 Apr 21.
Published in final edited form as: Bioorg Med Chem Lett. 2005 May 16;15(10):2633–2635. doi: 10.1016/j.bmcl.2005.03.063

Table 1.

Antibacterial activity of ECg, 6-8 and in combination with oxacillin against methicillin resistant Staphylococcus aureus (MRSA) strains

MRSA strain MIC (mg/L)a
 Oxacillin MIC (mg/L)a
ECg 7 8 — b ECg 7b,c 8b,c
BB 568 256 256 256 256/256 ≤0.5 4/8 64/64
EMRSA 15 256 256 256 32/32 ≤0.5 ≤0.5/≤0.5 2/4
EMRSA 16 128 128 128 512/512 ≤0.5 1/1 256/512
a

MIC’s were determined in Mueller-Hinton broth + 2% salt at 35 °C after 24 h incubation.

b

Data for two separate experiments are shown.

c

Fixed concentration of 25 mg/L.