Table 3.
Neutralizing titers achieved following vaccination with
| Vaccine administered | Reciprocal neutralizing titer (log2) |
||
|---|---|---|---|
| Pre-bleed and Post-dose 1 | Post-dose 2 | Post-dose 3 | |
| Recombinant protein vaccine (Bisht et al., 2005) | |||
| Spikea + adjuvantb | <3 | 8.3 | 10.0 |
| L1Rc + adjuvantb | <3 | <3 | <3 |
| Inactivated, whole-virus vaccine (Stadler et al., 2005) | |||
| BPL-SARSd + saline | <3 | <3 | 6.0 |
| BPL-SARSd + adjuvante | <3 | 6.5 | 9.3 |
| BPL-Flud + adjuvante | <3 | <3 | <3 |
a
10 μg/dose, s.c.
b
Adjuvant = QS21 (saponin).
c
L1R = vaccinia virus L1R protein.
d
5 μg total protein/dose, s.c.
e
Adjuvant = MF59 (oil-in-water emulsion).