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. 2008 Apr 30;3(4):e2041. doi: 10.1371/journal.pone.0002041

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Comparison between (A, C) the bead-based assay and (B, D) the bead-free reaction in 10% FBS. (C, D) Lineweaver-Burk (double reciprocal) plots of the BoNT/A reaction rate as a function of the substrate (SNAPtide) concentration. Note different y-axis scales. The solid lines represent linear regression fits.