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. Author manuscript; available in PMC: 2009 Mar 31.
Published in final edited form as: Eur J Pharmacol. 2008 Feb 5;583(1):73–83. doi: 10.1016/j.ejphar.2008.01.025

Figure 1.

Figure 1

Induction of continuous high frequency epileptiform discharges or in vitro status epilepticus like activity in cultured hippocampal neurons during exposure to low Mg2+ solution. A. Representative current clamp recording from a control neuron showing occasional spontaneous action potentials. B and C. Representative current clamp recordings showing induction of tonic high frequency epileptiform bursts (in vitro status epilepticus) from neurons subjected to 2 and 8-h of low Mg2+ treatment respectively. Tonic high frequency spiking was observed at all the durations of SE. The results shown were representative of over 20 recordings.