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. 2008 Apr 30;3(4):e2069. doi: 10.1371/journal.pone.0002069

Figure 6. E2 effect on insulin content in ERαKO and ERβKO mice.

Figure 6

(A) Insulin content obtained in cultured islets from wild-type and ERαKO mice exposed to either vehicle or 1 nM E2. Data obtained from 4 animals for experiments performed with wild-type mice and from 6 animals for experiments performed with KO mice, *p<0.001 compared to vehicle (B) Insulin content obtained in cultured islets from wild-type and ERβKO mice exposed to either vehicle or 1 nM E2. Data obtained from 2 animals for experiments performed with wild-type mice and 2 animals for experiments performed with KO mice, *p<0.05 compared to vehicle (C) Insulin content obtained in cultured islets from wild-type and ERαKO mice exposed to either vehicle or 1 nM BPA. Data from 4 animals for experiment performed with wild-type mice and 3 animals for experiment performed with KO mice, *p<0.001 compared to vehicle (D) Insulin content obtained in cultured islets from wild-type and ERβKO mice exposed to either vehicle or 1 nM BPA. Data from 4 animals for experiment performed with wt mice and 4 animals for experiment performed with KO mice, *p<0.001 compared to vehicle.