Table 1. Overview of NLR family members according to their domain organization.
| Nomenclature | Synonyms | Domain structure | Chrom. location | Genebank |
| CARD domain | ||||
| NOD1 | NLRC1,CARD4 | CARD-NACHT-WH-SH-LRR | 7p14.3 | AF126484 |
| NOD2 | NLRC2, CARD15 | CARD-CARD-NACHT-WH-SH-LRR | 16q12.1 | AF178930 |
| CIITA type1 | NLRA | CARD-(X-NACHT-WH-SH-LRR) | 16p13.13 | AF000002 |
| PYRIN domain | ||||
| NALP1 | NLRP1, CARD7 | PYD-NACHT-WH-SH-LRR-FIIND-CARD | 17p13.2 | AB023143 |
| NALP2 | NLRP2, Pypaf2 | PYD-NACHT-WH-SH-LRR | 19q13.42 | AK000517 |
| NALP3 | NLRP3, Pypaf1 | PYD-NACHT-WH-SH-LRR | 1q44 | AF054176 |
| NALP4 | NLRP4, Pypaf4 | PYD-NACHT-WH-SH-LRR | 19q13.43 | AF479747 |
| NALP5 | NLRP5, NOD14, Pypaf8 | PYD-NACHT-WH-SH-LRR | 19q13.43 | AY154460 |
| NALP6 | NLRP6, Pypaf5 | PYD-NACHT-WH-SH-LRR | 11p15.5 | AF479748 |
| NALP7 | NLRP7, NOD12, Pypaf3 | PYD-NACHT-WH-SH-LRR | 19q13.42 | AF464765 |
| NALP8 | NLRP8, NOD16 | PYD-NACHT-WH-SH-LRR | 19q13.43 | AY154463 |
| NALP9 | NLRP9, NOD6 | PYD-NACHT-WH-SH-LRR | 19q13.43 | AY154464 |
| NALP10 | NLRP10, NOD8, Pynod | PYD-NACHT-WH-SH | 11p15.4 | AY154465 |
| NALP11 | NLRP11, NOD17, Pypaf6 | PYD-NACHT-WH-SH-LRR | 19q13.42 | AY095145 |
| NALP12 | NLRP12, Pypaf7, RNO | PYD-NACHT-WH-SH-LRR | 19q13.42 | AY095146 |
| NALP13 | NLRP13, NOD14 | PYD-NACHT-WH-SH-LRR | 19q13.42 | AY154468 |
| NALP14 | NLRP14 | PYD-NACHT-WH-SH-LRR | 11p15.4 | BK001107 |
| BIR domain | ||||
| NAIP | NLRB1, BIRC1 | BIR-NACHT-WH-SH-LRR | 5q13.1 | U19251 |
| untypical CARD | ||||
| Ipaf | NLRC4, Card12, Clan | Card?-NACHT-WH-SH-LRR | 2p22-p21 | AF376061 |
| NOD4 | NLRC5, NOD27 | Card?-NACHT-WH-SH-LRR | 16q13 | AF389420 |
| NOD3 | NLRC3 | Card?-NACHT-WH-SH-LRR | 16p13.3 | BK001112 |
| undefined | ||||
| NOD5 | NLRX1, NOD26, NOD9 | X-NACHT-WH-SH-LRR | 11q23.3 | AB094095 |
| CIITA | NLRA | X-NACHT-WH-SH-LRR | 16p13.13 | U18259 |
Protein name and synonyms (new synonyms in bold), accession number, and chromosomal location according to http://www.genenames.org/genefamily/nlr.php followed by domains as defined by FFAS. CARD, caspase activation and recruitment domain; PYD, pyrin; NACHT, domain present in NAIP, CIITA, HET-E, TP-1; NALP, NACHT-LRR-PYD-containing protein; WH, winged helix domain; SH, superhelical domain, LRR, leucine-rich repeats.