Figure 1.

Representation of the fifteen lowest energy poses of urokinase kringle domain on αIIbβ3 in the open conformation. The α and β chains of αIIbβ3 are shown as pale pink and yellow spheres, respectively. The stretch of aminoacids homologous to the α325 peptide are highlighted in magenta, the stretch homologous to β1P1 in orange, and the one homologous to β1P2 in yellow.

Ribbons represent every ligand positions after the rigid-body simulations. A spectrum of different shadows of red, green, blue, cyan were used going from lowest to highest energy solutions.