Figure 1. Human memory helper T cells produce significantly higher levels of IL-17.
(a,b). Isolated human naïve and memory CD4+ T cells were stimulated with plate-bound anti-CD3 and anti-CD28 for 24 hours. IL-17 production was detected by ELISA immunoassay kits. A representative result is shown in panel a and data from five healthy donors are shown in panel b, where the horizontal line indicates geometric mean. Statistical significance was calculated based on geometric mean using paired t-test.