Distribution of mutational effects on sleep. Pink, 99.9% C.I. threshold; dark blue, 99% C.I. threshold; light blue, 95% C.I. threshold. (A) Male 24-hr sleep time: 99.9% C.I. threshold, 168.4 min; 99% C.I. threshold, 111.5 min; 95% C.I. threshold, 84.8 min. (B) Female 24-hr sleep time: 99.9% C.I. threshold, 197.9 min; 99% C.I. threshold, 131.0 min; 95% C.I. threshold, 99.7 min. (C) Male nighttime sleep: 99.9% C.I. threshold, 105.0 min; 99% C.I. threshold, 69.5 min; 95% C.I. threshold, 52.9 min. (D) Female nighttime sleep: 99.9% C.I. threshold, 124.0 min; 99% C.I. threshold, 82.1 min; 95% C.I. threshold, 62.5 min. (E) Male daytime sleep: 99.9% C.I. threshold, 88.6 min; 99% C.I. threshold, 58.6 min; 95% C.I. threshold, 44.6 min. (F) Female daytime sleep: 99.9% C.I. threshold, 108.2 min; 99% C.I. threshold, 71.6 min; 95% C.I. threshold, 54.5 min.