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. 2008 Apr;178(4):2417–2427. doi: 10.1534/genetics.107.085332

TABLE 3.

Average value of summary statistics for forward simulations with and without selfing

FORWSIMe
msf
2Na Generations ub rc sd E[S]g E[H]h E[S] E[H]
1,000 10,000 0.0100 0.0100 0.00 71.250 16.066 71.016 15.916
1,000 20,000 0.0182 0.1000 0.90 70.687 15.968 71.016 15.916
1,000 20,000 0.0196 0.5000 0.98 70.804 15.586 71.016 15.916
1,000 10,000 0.1000 0.1000 0.00 708.614 19.612 706.603 19.538
1,000 20,000 0.1333 0.2000 0.50 711.662 19.563 706.603 19.538
a

Total number of chromosomes under the standard neutral Wright–Fisher model with constant population size and uniform mutation and recombination rates.

b

Per-generation per-sequence mutation rate.

c

Per-generation per-sequence recombination rate.

d

Probability of selfing.

e

FORWSIM is our forward simulation program written in C++ and is freely available at http://people.cornell.edu/pages/bp85.

f

ms is a C program that simulates data sets under the coalescent framework and is freely available at http://home.uchicago.edu/∼rhudson1/source.html. ms was run with the population crossing-over rate ρ = 4Nr and population mutation rate θ = 4Nu.

g

Total number of SNPs for a sample size of 20 chromosomes. Average values are based on 1000 simulations.

h

Number of distinct haplotypes. Average values are based on a sample of 20 chromosomes and 1000 simulations.