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(A) Time-course analysis of folding in the presence of PDI F449R, the early stages being shown in (B). PDI F449R was incubated with GSH/GSSG and the intermediates were analyzed as described in Figure 3 ▶. For the sake of clarity, error bars are not shown. nS represents intramolecular disulfide bonds, nG mixed disulfides with glutathione, and nH free thiols.
