Table 1.

Hydrogen bond occupancy for the backbone atoms in the β sheet region during the last 1.2 nsec

Strands	WT-TTR		V30M-TTR		L55P-TTR
	Donor-acceptor	%	Donor-acceptor	%	Donor-acceptor	%
C & B	V30-G47	99.8	M30-G47	100.0	V30-G47	99.9
	G47-V30	98.0	G47-M30	99.8	G47-V30	96.0
	V32-A45	99.8	V32-A45	100.0	V32-A45	100.0
	A45-V32	98.4	A45-V32	97.3	A45-V32	99.1
	R34-E42	100.0	R34-E42	100.0	R34-E42	100.0
	E42-R34	97.4	E42-R34	96.3	E42-R34	59.5
	F44-V32	96.5	F44-V32	99.5	F44-V32	78.0
B & E	H31-E72	99.6	H31-E72	100.0	H31-E72	100.0
	E72-H31	100.0	E72-H31	100.0	E72-H31	99.9
	F33-K70	100.0	F33-K70	100.0	F33-K70	99.8
	K70-F33	99.9	K70-F33	100.0	K70-F33	100.0
	K35-I68	100.0	K35-I68	99.9	K35-I68	99.9
E & F	G67-A97	99.3	G67-A97	88.3	G67-A97	99.5
	A97-G67	99.4	A97-G67	99.8	A97-G67	99.6
	Y69-F95	100.0	Y69-F95	100.0	Y69-F95	100.0
	F95-Y69	100.0	F95-Y69	100.0	F95-Y69	100.0
	V71-V93	99.8	V71-V93	99.8	V71-V93	99.9
	V93-V71	91.6	V93-V71	99.3	V93-V71	99.9
	I73-A91	98.9	I73-A91	98.9	I73-A91	98.8
	A91-I73	99.9	A91-I73	100.0	A91-I73	99.8
D & A	V14-L55	86.6	V14-L55	99.5	V14-P55	0.0
	L55-V14	96.1	L55-V14	99.4	P55-V14	0.0
A & G	M13-Y105	99.0	M13-Y105	100.0	M13-Y015	52.8
	K15-I107	99.4	K15-I107	99.5	K15-I107	77.1
	L17-A109	99.9	L17-A109	99.8	L17-A109	97.9
	I107-M13	99.5	I107-M13	99.9	I107-M13	32.3
	A109-K15	83.6	A109-K15	98.8	A109-K15	65.6
	L111-L17	99.8	L111-L17	100.0	L111-L17	65.1
G & H	R104-T123	100.0	R104-T123	100.0	R104-T123	100.0
	T123-R104	99.6	T123-R104	99.5	T123-R104	99.5
	T106-V121	63.8	T106-V121	100.0	T106-V121	99.9
	V121-T106	61.6	V121-T106	99.3	V121-T106	95.6
	A108-T119	60.4	A108-T119	97.5	A108-T119	0.0
	T119-A108	94.5	T119-A108	94.3	T119-A108	0.0
	L110-S117	96.1	L110-S117	99.3	L110-S117	90.6
	S117-L110	99.3	S117-L110	99.8	S117-L110	91.1