Table 3.
Age-related macular degeneration | Normal vision | |||||||
---|---|---|---|---|---|---|---|---|
All AMD subjects (n=13) | AMD subjects with foveal fixation (n=4) | AMD subjects with eccentric fixation (n=9) | p-value (foveal vs eccentric fixation In AMD) | Central vision (n = 5) | 10° inferior vision (n= 11) | p-value (central vs inferior vision in NV) | ||
Visual span | Visual-span size (bits) | median: 23.9 (24.8 ± 8.2) (range: 12.5–40.6) | median: 33.6 (30.1 ± 12.4) (range: 12.5–40.6) | median: 20.6 (22.5 ± 4.8) (range: 16.4–30.6) | 0.26 | median: 40.8 (41.2 ± 1.5) (range: 36.7–43.8) | median: 29.0 (28.5 ± 2.8) (range: 24.3–32.5) | 0.001 |
Temporal threshold (ms) | median: 623.0 (1003.8 ± 926.1) (range: 103.1–3056.3) | median: 548.0 (536.6 ± 27.8) (range: 504.8–556.9) | median: 815.1 (1159.6 ± 1034.4) (range: 103.1– | 0.48 | 13 * | median: 100.3 (97.0 ± 34.2) (range: 60.4–129.9) | 0.001 | |
Information transfer rate (bits per sec) | median: 29.5 (79.8 ± 108.7) (range: 9.3–406.2) | median: 82.4 (147.3 ± 175.4) (range: 18.2–406.2) | median: 29.2 (49.9 ± 53.8) (range: 9.3–180.7) | 0.26 | median: 407.7 (411.7 ± 15.4) (range: 397.0–437.5) | median: 290.5 (284.7 ± 28.2) (range: 242.5–25.4) | 0.001 | |
Reading | RSVP reading speed (log wpm) | median: 2.09 (2.09 ± 0.29) (range: 1.71–2.46) | median: 2.17 (2.13 ± 0.38) (range: 1.71–2.46) | median: 2.09 (2.07 ± 0.26) (range: 1.75–2.40) | 0.71 | median: 2.52 (2.54 ± 0.07) (range: 2.45– 2.65) | median: 1.93 (1.96 ± 0.35) (range: 1.37–2.42) | <0.001 |
Bracket in the cell indicates the minimum and maximum.
PRL = preferred retinal location
13 ms represents the upper-bound on the temporal thresholds for the NV subjects at central vision.