. 2003 Aug;12(8):1706–1718. doi: 10.1110/ps.0301103

Table 4.

Overall concordance of structural phenotype with experimental phenotype for blind predictions

	PhenoSense^a		Antivirogram^b
Structural Prediction	S	R	S	R
S	196	13	112	19
R	7	41	7	43
E^c	6	3	4	6

^a 266 comparisons for 46 samples and 6 PIs. The overall agreement between structural phenotype and PhenoSense prediction of PI resistance was 92.2% (kappa = 0.756, P < 0.00001). (S) Sensitive; (R) resistant; (E) equivocal.

^b 191 comparisons for 32 samples and 6 PIs. The overall agreement between structural phenotype and Antivirogram prediction of PI resistance was 85.6% (kappa = 0.666, P < 0.00001).

^c Equivocal assignments where the change in binding energy was between the lower and the upper cutoffs. For equivocal structural predictions, genotypic resistance assignments agreed with the phenotypic predictions in 8 of 9 cases (PhenoSense) and 6 of 10 cases (Antivirogram).