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. 2003 Sep;12(9):2073–2080. doi: 10.1110/ps.0393503

Table 1.

Refolding and biophysical analysis of the 70 protein samples that are insoluble in vivo

gi#a No. of Residues % Refolded CD result HSQC
Saccharomyces cerivisiae
    6322622 116 100 α-helical poor
    6325453 109 100 β-sheet poor
    6320900 107 100 β-sheet unfolded
    6324270 110 0
    6322568 123 0
    6325316 128 0
    6321730 73 0
    6319465 145 0
    6321928 148 50 α-helical poor
    6321669 137 100 random coil unfolded
    14318509 148 0
    6324454 102 100 dilute poor
    6321245 103 100 dilute poor
    6319472 104 80 α-helical poor
    10383788 136 100 random coil unfolded
    6321445 84 100 unusual poor
    6322784 147 0
    6320815 87 100 α-helical poor
    14318500 117 0
    6321306 111 100 α-helical poor
    6319745 105 80 random coil unfolded
    6323397 110 60 random coil poor
    6321317 126 0
    6322326 105 100 no signal poor
        6321850 130 100 unusual poor
    6323850 74 0
    6321037 122 100 unusual poor
    6323326 124 100 random coil unfolded
    6324523 106 80 α-helical dilute
    6324941 117 0
    83189 146 5
    6324001 146 100 α-helical poor
    6325210 99 50 α-helical unfolded
    6322681 137 80 uunusual good
    6320760 122 5
    6323190 114 10
    6320458 149 5
    6319609 133 100 α-helical poor
    6325115 105 50 α-helical good
    10383803 146 50 β-sheet dilute
    7839146 126 0
    6322262 108 5
Thermotoga maritima
    4981121 151 100 α-helical promising
    4981364 101 0
    4981437 101 100 unusual poor
    4981475 118 100 α-helical 2.8-Åb
    4981497 135 50 α-helical poor
    4981533 101 0
    4981568 111 0
    4981614 114 0
    4981889 111 100 random coil unfolded
    4981890 144 0
    4982100 92 80 β-sheet good
    4982192 121 0
    4982245 117 0
Methanobacterium thermoautotrophicum
    2621100 114 80 α-helical dilute
    2621252 127 100 random coil unfolded
    2621282 125 5
    2621294 138 30
    2621458 126 50 α-helical promising
    2621459 148 0
    2622053 106 50 α-helical poor
    2622351 148 100 β-sheet poor
    2622414 63 50 α-helical poor
    2622420 136 60 α-helical poor
    2622488 132 100 α-helical good
    2622555 169 90 α-helical dilute
    2622607 148 0
    2622899 135 100 α-helical good
    2621045 50 100 random coil unfolded

aNational Center for Biotechnology Information (NCBI) protein identification number (PID).

bThis sample produced a poor HSQC, but formed native crystals that diffract to 2.8 Å.