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. Author manuscript; available in PMC: 2008 Apr 21.
Published in final edited form as: Free Radic Biol Med. 2006 Jan 9;40(4):555–556. doi: 10.1016/j.freeradbiomed.2005.12.007

Figure 1.

Figure 1

Ascorbate is an excellent one-electron reducing agent that can spare tocopherol. AscH can intercept the primary oxidants (In(ox)) that can initiate free radical-mediated lipid oxidation, right. This would spare TOH as the need for its reducing capacity would be lessoned. AscH can also recycle tocopherol by reducing TO back to TOH, not allowing TO to be oxidized further and then in turn go on to form irreversible products and be lost.