Table 2.
Cost of Care during ALLHAT and Estimated Lifetime Cost
| Mean cost chlorthalidone | Increase in cost (95%CI) versus chlorthalidone | ||
|---|---|---|---|
| Amlodipine | Lisinopril | ||
| In trial | |||
| Drug cost ($) | |||
| Study drug | 618 | 2,681 (2,649, 2,714) | 1,383 (1,360, 1,405) |
| Other antihypertensive drug | 1,168 | 17 (−15, 48) | 241 (209, 277) |
| Total drug cost | 1,786 | 2,698 (2,631, 2,762) | 1,624 (1,586, 1,664) |
| Hospitalization ($) | |||
| Heart failure | 368 | 68 (20, 123) | 18 (−34, 71) |
| Ischemic heart disease | 1,876 | 58 (−95, 216) | 87 (−67, 253) |
| Stroke | 240 | −3 (−45, 37) | 54 (6, 100) |
| Other cardiovascular | 988 | 1 (−101, 101) | 50 (−47, 148) |
| Cancer | 1,069 | 26 (−67, 113) | 225 (130, 307) |
| Other noncardiovascular | 4,063 | −320 (−558, −40) | 138 (−150, 449) |
| Total hospitalization cost | 8,604 | −170 (−535, 235) | 572 (150, 1038) |
| Outpatient visit cost ($) | 1,057 | −9 (−34, 15) | 28 (−3, 57) |
| Total in trial cost ($) | 11,447 | 2,519 (2,154, 2,934) | 2,224 (1,797, 2,692) |
| Lifetime cost ($) | 53,536 | 4,802 (3,862, 6,092) | 3,700 (2,676, 5,000) |
Cost of care discounted at 3% per year. Individual costs may not sum to totals as a result of rounding.