Table 1.
Human brain material in tissue array A
Donor
|
Fixation
|
|||||
---|---|---|---|---|---|---|
Number | Age | Sex | PMI (days) | Time | Fixative | Diagnosis |
1 | 20 G.W. | NA | 3 | 2 days | 4% Lillies | Spontaneous abortion, acute infection |
2 | 16 G.W. | NA | NA | 10 years | Picric acid | Provoked abortion, causa socialis |
3 | 20 G.W. | NA | NA | 10 years | 4% Lillies | Provoked abortion, suspected syndrome |
4 | 40 G.W. | M | 1 | 2½ months | 4% Lillies | Stillborn, ischemia during delivery |
5 | 1 month | M | NA | 10 years | 9% Lillies | DiGeorge syndrome |
6 | 82 years | M | 2 | 1 day | 4% Lillies | Ruptured abdominal aneurism of aorta |
7 | 75 years | M | <1 | 1 day | 4% PFA | NA |
8 | 62 years | F | 4 | 3 months | 4% Lillies | NA |
9 | 88 years | F | 3 | 4 months | 4% Lillies | Heart failure |
10 | 93 years | F | NA | 10 years | 9% Lillies | Pulmonary emboli |
From the fetal brain material (Donors 1–3), specimens were sampled from the lateral telencephalic wall including the cortical plate, intermediate zone, and subventricular zone. From the brains from newborns (Donors 4 and 5), specimens from the neocortex and subcortical white matter were sampled from the frontal region, and in material from adults (Donors 6–10), specimens were sampled from the neocortex and subcortical white matter from the frontal or parietal lobes. PMI, postmortem interval; G.W., gestational week; NA, not available; M, male; PFA, paraformaldehyde in 0.15 M Sørensens phosphate buffer, pH 7.4; F, female.