Table 1.
List of genes with elevated expression within Min tumors
| Gene name | Symbol | Detection | Expression | Distribution in non-neoplastic tissues |
|---|---|---|---|---|
| Matrix metalloproteinase 7 | MMP7 | SSH | Paneth | Paneth cells of small intestine |
| Defensin α1 | DefA1 | SSH | Paneth | Neutrophils, Paneth cells of small intestine |
| Lysozyme | Lyz | SSH | Paneth | Paneth cells of small intestine |
| Heterogeneous nuclear ribonucleoprotein A1 | hnrPA1 | SSH | PZA | Nuclei of eukaryotic cells |
| Heat shock protein 70 | HSP70 | SSH | PZA | Muscle, heart, esophagus, brain, testis |
| β-Tubulin 5 | Tubb5 | SSH | PZA | Microtubules |
| Synaptophysin-like protein | Sypl | MA | PZA | Synaptic vesicle protein, pancreas |
| Stathmin 1 | Stmn1 | MA | PZA | Universal, high in mitotic cells |
| CD24 antigen | CD24 | MA | PZA | B-lineage cells, granulocyte |
| Arachidonate 12-lipoxygenase | Alox12 | MA | PZA | White blood cells |
| Protein expressed in non-metastatic cells | NME4 | SSH | PZA | Prostate, heart, liver, small intestine, and skeletal muscle |
| Clusterin | Clu | SSH | Tumor | Widely distributed |
| Tissue-type plasminogen activator | tPA | SSH | Tumor | Endothelial cells; nervous system, regions with cell migration |
| Wnt inhibitory factor 1 | WIF1 | MA | Tumor | Retina, lung, mammary gland |
| Caspase 6 | Casp6 | MA | Tumor | Apoptotic cells |
| MARCKS-like protein | MLP | MA | Tumor | Widely distributed, high in testis and uterus |
| Tescalcin | Tsc | MA | Tumor | Heart, brain, and stomach |
| SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2 | Spock2 | MA | Tumor | Brain, thymus, peripheral blood leukocyte |
| Lysosomal membrane glycoprotein 2 | LAMP2 | MA | Tumor | Placenta, lung, and liver |
| Potassium voltage-gated channel, Isk-related subfamily, gene 3 | KCNE3 | MA | Tumor | Muscle |