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. 1999 Jan;96(1):10–15. doi: 10.1046/j.1365-2567.1999.00659.x

Figure 6.

Figure 6

(a–c) Movement disorder rate during the course of R. aurantiacus infection in mice treated with NRG (open circles, control), anti-CD4 (open squares), anti-CD8 (open triangles) and both mAbs (closed circles). (a) Vertical headshake; (b) turn-round gate; and (c) hemiparesis. Each group comprised 20 mice. Only simultaneous administration of anti-CD4 and anti-CD8 mAb significantly inhibited the appearance of movement disorders: (a), P <0·01; (b), P <0·05; and (c) P <0·01. (d–f) Infected mice treated with NRG (open circles), rat IgG2b (open squares), rat IgG2a (open triangles) and both rat IgG2a and IgG2b (closed cicles). (d) Vertical headshake; (e) turn-round gate; and (f) hemiparesis. Each group comprised 10 mice. Treatment with isotypic immunoglobulin did not affect the appearance of movement disorders.