Figure 3.

FIV-specific suppressor activity during acute infection with FIV_GL-8. Mitogen-activated lymphoblasts were prepared from the blood (a and b) and lymph nodes (c and d) of two cats, 16 weeks postinfection with FIV_GL-8, and were cocultured with either FIV_PET-infected (▪) or FIV_GL-8-infected (•) MYA-1 cells at ratios of 4:1 (---), 2:1 (– – –), and 1:1 (· · ·). Control cultures contained FIV-infected MYA-1 cells alone (——). Replication of FIV was indicated by the detection of viral p24 in the culture supernatant by ELISA. The results shown represent the mean OD values at 650 nm measured for the two cats ± 2 SD, error bars are not discernible where the SD is small.