Figure 2.
Effect of R. sanguineus tick infestations on Con A-induced cell proliferation in mice. Lymph node cells from mice infested once (1×Inf), four times (4×Inf) or non-infested (Control) with ticks were cultured (5×105 cells per well) with or without Con A (2 μg/ml) and assayed for cell proliferation by methyl-[3H]-thymidine incorporation. A stimulation index was calculated for each experimental group as described in the Material and Methods. Results are shown as mean of Stimulation Index ± SD from two independent experiments.