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. 1999 Mar;96(3):372–380. doi: 10.1046/j.1365-2567.1999.00684.x

Figure 2.

Figure 2

Tolerance induction by DNFB-derivatized Mφ in presensitized mice. All groups of animals but the negative control (Group E) were sensitized epicutaneously with DNFB. Seven days after sensitization animals from Group A received injections of 5000 DNFB-derivatized Mφ#63. Groups B and C received injections of 5000 Mφ#59 and Mφ#59 treated with TGF-β2, respectively. Groups D and E did not receive any treatment at this time. All groups of mice were ear challenged with DNFB 5 days after injection of Mφ. CH reactions were evaluated by ear swelling measurements at 24 and 48 hr. The 24-hr ear swelling measurements are shown. * indicates that the mean value is significantly less than the positive control (P < 0·00005).