Skip to main content
. 1999 Mar;96(3):416–423. doi: 10.1046/j.1365-2567.1999.00699.x

Figure 1.

Figure 1

Flow cytometric analysis of CD4+ and CD8+ T lymphocytes in peripheral blood (a) and spleen (b) for four different groups of rats. NO: non-sensitized and OA exposed, n =7; SScd8: sensitized, anti-CD8 antibody treated and saline exposed, n =4; SOsham: sensitized, mouse immunoglobulin G (IgG) treated and 1% ovalbumin (OA) challenged, n =10; and SOcd8: sensitized, anti-CD8 antibody treated and OA exposed, n =10. Cell number is expressed as percentage of total lymphocytes measured by expression of CD3+ T cells. There was a significant decrease in the proportion of splenic CD4+ T cells in the sensitized and OA-exposed rats. CD8+ cells were reduced to less than 1% by anti-CD8 treatment in both peripheral blood and spleen. †P < 0·03 compared with groups SScd8 and SOcd8; **P < 0·04 compared with groups NO and SScd8. Data are shown as mean±SEM.