Figure 1.

Dose dependency of the effects of GT1b on human peripheral blood mononuclear cells (PBMC). PBMC from one healthy donor were cultured in triplicate in the presence of the indicated doses of GT1b. The production of IgG, IgM and IgA was determined by enzyme-linked immunosorbent assay (ELISA) on day 5, and [³H]TdR uptake was determined on day 4. Values are expressed as mean±SD of triplicate cultures. *P < 0·0001vs. control cultures. The data are representative of four separate experiments using PBMC from four different donors.