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. 1999 Sep;98(1):98–103. doi: 10.1046/j.1365-2567.1999.00849.x

Figure 6.

Figure 6

Regulation of cytokine production in antigen-primed CD4+ T cells by macrophages purified from mice treated in vivo with sulfasalazine. DBA/2 mice were treated in vivo with either sulfasalazine (1 mg, i.p.) or saline. After 24 hr, macrophages were purified and incubated with KLH-primed CD4+ T cells and KLH (10 μg/ml). After 4 days, culture supernatants were harvested 4 days and assayed for IL-12 (a), IFN-γ (b) and IL-4 (c) content by ELISA. The values represent the mean±SD of triplicate determinations of two separate experiments.