Table 2.
Incidence of tubal abnormalities in ICAM‐1–/– and ICAM‐1+/+ mice after multiple genital infections with C. trachomatis
| Group/animal # | Observed pathology* |
|---|---|
| ICAM‐1−/− mice: | |
| #1 | Bilateral hydrosalpinx |
| #2 | Bilateral hydrosalpinx |
| #3 | Left tubal hydrosalpinx and inflamed ovaries |
| #4 | Left tubal hydrosalpinx |
| #5 | No abnormalities observed |
| #6 | Right tubal hydrosalpinx |
| ICAM‐1+/+ mice: | |
| #1 | No abnormalities observed |
| #2 | No abnormalities observed |
| #3 | No abnormalities observed |
| #4 | No abnormalities observed |
| #5 | Right tubal hydrosalpinx |
| #6 | No abnormalities observed |
*
For gross pathological studies, ICAM‐1−/− and ICAM‐1+/+ mice were infected four times over a period of 54 weeks to increase the incidence of tubal abnormalities. The reproductive system (between the uteri and ovaries) was examined visually for hydrosalpinx formation and haemorrhagic lesions on one or both uterine tubes (i.e. unilateral or bilateral hydrosalpinx). Table 2 summarizes the results obtained from six mice in each group.