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DNA fragmentation in LL‐CPK1 cells after incubation with Bence–Jones proteins (BJPs). LL‐CPK1 cells were incubated with BJPs and the DNA fragments present in the lysate were detected by the method of Hockenbery et al.17 Lane 1, 2 μm of bovine serum albumin (BSA); lanes 2–4, 2, 1 and 0·25 μm of cytotoxic BJP, respectively; lane 5, 2 μm of non‐cytotoxic BJP; lane 6, 100‐bp DNA ladder marker (Amersham Pharmacia Biotech, Tokyo, Japan).
