Figure 2.
Interleukin (IL)-2 production (following infection with influenza) by splenocytes from young and old mice fed diets containing 30 parts per million (ppm) (control) or 500 ppm (supplemented) vitamin E for 8 weeks. Splenocytes (5 × 106 cells/well) were stimulated with concanavalin A (Con A) (5 µg/ml) for 24 hr. Values are expressed as mean + SEM, n = 4–9. *Significantly different from mice fed the control diet, as determined by Fisher's least significant test at P < 0·05. †Significantly different from day 0 of the same age and diet group, as determined by Fisher's least significant test at P < 0·05. ‡Significantly lower than young mice of the same diet and postday at P < 0·05. YC, young mice fed the control diet; YE, young mice fed the vitamin E-supplemented diet; OC, old mice fed the control diet; OE, old mice fed the vitamin E-supplemented diet.