Table 1.

Effect of vitamin E supplementation on prostaglandin E₂ (PGE₂) production (ng/ml) by macrophages (Mφ) from uninfected (day 0) young and old C57BL/6NCrlBR mice

	Young		Old
	Control	Vitamin E	Control	Vitamin E
Medium	2·09 + 0·48	1·80 + 0·21	2·61 + 0·08	2·00 + 0·09
LPS stimulated	12·55 + 1·08	14·94 + 1·16	21·91 + 1·43†	12·69 + 0·52*

Values are expressed as mean + SEM, n = 8.

^*Significantly different from old mice fed the control diet, as determined by Fisher's least significant test (P < 0·05).

^†Significantly different from young mice, as determined by Fisher's least significant test (P < 0·001).

LPS, lipopolysaccharide.