Figure 3.
Pertussis toxin (PTX)-induced primed U937 cell adhesion to vitronectin (5 µg/ml)-coated plates. U937 cells were treated with PTX holotoxin (10 µg/ml) or PTX B-oligomer (3 µg/ml) in the presence or absence of monoclonal antibodies (mAbs) directed against domain II of the urokinase receptor (uPAR) (2 µg/ml) or αv integrin (1 : 100 dilution). Each value represents the mean ± SEM of four to six experiments performed in duplicate and is expressed as the percentage of control adherent responses to PTX. *P < 0·05 compared with primed U937 cell controls. D3, 1,25-(OH)2 vitamin D3; TGF-β1, transforming growth factor-β1.