Table 1.
Production of cytokines and MMP-9 by MoDCs (ng/ml)
| Treatment | IL-1β | TNF-α | IL-10 | IL-12 | MMP-9 |
|---|---|---|---|---|---|
| Exp. 1 | |||||
| Non-treated | 0·0 | 0·0 | 0·0 | 0·0 | 22·4 |
| 300 μm Ni | 0·0 | 18·1 | 0·0 | 0·0 | 21·1 |
| 30 μm DNCB | 0·0 | 0·0 | 0·0 | 0·0 | 20·2 |
| 100 μm DNCB | 0·0 | 0·0 | 0·0 | 0·0 | 21·4 |
| 10 μm DNFB | 0·0 | 0·0 | 0·0 | 0·0 | 25·8 |
| 30 μm DNFB | 0·0 | 0·0 | 0·0 | 0·0 | 24·9 |
| exp. 2 | |||||
| Non-treated | 0·0 | 36·8 | 23·0 | 0·0 | 61·2 |
| 300 μm Ni | 0·0 | 57·9 | 36·3 | 0·0 | 57·4 |
| Exp. 3 | |||||
| Non-treated | 0·0 | 0·0 | 0·0 | 0·0 | 10·9 |
| 30 μm DNCB | 0·0 | 49·0 | 0·0 | 0·0 | 10·4 |
| 30 μm DNCB | 0·0 | 0·0 | 0·0 | 0·0 | 14·9 |
| 30 μm DNCB | 0·0 | 0·0 | 0·0 | 0·0 | 14·5 |
| Exp. 4 | |||||
| Non-treated | ND | 0·0 | 0·0 | ND | ND |
| 100 μm Ni | ND | 10·0 | 0·0 | ND | ND |
| 300 μm Ni | ND | 10·0 | 0·0 | ND | ND |
| 1000 μm Ni | ND | 80·0 | 0·0 | ND | ND |
| 30 μm DNCB | nd | 0·0 | 0·0 | ND | ND |
| 100 μm DNCB | ND | 5·0 | 0·0 | ND | ND |
nd, not determined.