Table 2.
Induction coefficients of cytokine transcription (ICT) in porcine peripheral blood mononuclear cells (PBMC)
| Con A | PRV (inactivated) | |||||||
|---|---|---|---|---|---|---|---|---|
| Animals | IL-2 | IFN-γ | IL-4 | IL-10* | IL-2 | IFN-γ | IL-4 | IL-10 |
| Pig 1 (naive) | 29·6 | 11·9 | > 18·0 | + | NT† | NT | NT | NT |
| Pig 2 (naive) | 10·4 | 23·4 | > 12·0 | + | 0·6 | 0·9 | –‡ | + |
| Pig 3 (naive) | 15·3 | 19·9 | > 27·0 | + | 3·4 | 1·4 | – | + |
| Pig 4 (naive) | 12·2 | 6·4 | > 54·0 | + | 3·4 | 1·6 | – | + |
| Pig 5 (immune) | 11·9 | 13·2 | > 10·0 | + | 59·6 | 40·0 | – | + |
| Pig 6 (immune) | 17·1 | 45·0 | > 33·0 | + | 124·4 | 63·0 | – | + |
| Pig 7 (immune) | 13·1 | 45·4 | ++§ | + | 42·1 | 34·3 | – | + |
| Pig 9 (gC-DNA) | 30·7 | 6·6 | ++ | + | 2·1 | 2·6 | – | + |
| Pig 10 (gC-DNA) | 66·9 | 3·6 | ++ | + | 3·5 | 1·6 | – | + |
| Pig 15 (gC-DNA) | 12·7 | > 4·8 | ++ | + | 0·5 | – | – | + |
*
+ indicates the high constitutive transcription of interleukin (IL)-10, which did not increase significantly (also see the text).
†
Not tested.
‡
Not detectable.
§
The clear induction of IL-4 is indicated by ++, but the exact ICT was not determined.
gC, PRV glycoprotein gC; IFN-γ, interferon-γ; PRV, pseudorabies virus.