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Tolerance induction by adherent DC. Lewis rats were s.c. injected with MBP 68–86-pulsed adherent DC (n = 6) and floating DC (n = 6) from bone marrow at 1 × 106 DC/rat, respectively. After 4 weeks, these DC-treated rats and control EAE rats injected with PBS (n = 6) were immunized with MBP 68–86 and CFA. The graph shows mean clinical scores of EAE. These data are compiled from two independent experiments.
