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Reduced tumorigenicity of 4-1BBL-transfected NRS1 cells in syngeneic mice. C3H mice in groups of five were injected s.c. with the indicated number of NRS1 and 4-1BBL+ NRS1 cells (clone 5.13) and tumour growth was measured as described in the Materials and methods. The results are expressed as tumour volume of each mouse. Similar results were obtained in two other 4-1BBL+ NRS1 clones.
