Figure 2.

BI-specific T-cell proliferation is equivalently reduced for BITg T cells from normal and autoimmune NZB/W mice. Popliteal lymph node cells, pooled from three to four mice primed 14 days earlier, were cultured for 3 days with increasing concentrations of BI and pulsed overnight with [³H]TdR. Shown are the means of triplicate determinations. Results are representative of three independent experiments.