Figure 2.

Migration of CD4⁺ T lymphocytes towards stromal cell-derived factor-1α (SDF-1α) (a), or macrophage inflammatory protein-1α (MIP-1α) (b). CD4⁺ T lymphocytes were freshly isolated (open bars), incubated in medium only (black bars), or stimulated with IL-4 (grey bars) or IL-10 (half black bars). The data are taken from a single experiment, representative of four performed. All results were determined as described in the Materials and methods, are expressed as chemotactic index (C. I.) and based on triplicate determination of chemotaxis on each concentration of chemoattractant. The chemokine concentrations applied (ng/ml) are indicated.