Figure 7.

The effect of interleukin-12 (IL-12) gene transfer on the course of parasitaemia in BALB/c mice infected with Trypanosoma cruzi. BALB/c mice were treated with IL-12 or a control gene three times, at 0, 1 and 2 weeks after infection with 100 T. cruzi trypomastigotes. The levels of parasitaemia were estimated by counting blood drain and represent the mean ± SD for five mice. *Signifies a statistically significant difference (P < 0·05) between the group treated with pCAGGS (Control) and that treated with pCAGGS-IL-12 (IL-12). Results are representative of three independent experiments.