Table 3.
Age- and sex-adjusted relationships between ADAMTS-13, VWF and continuous coronary risk factors amongst controls. General linear models were fitted with transformed VWF or ADAMTS-13 as dependent variables (transformations as in Table 1). Beta coefficients associated with each factor are shown with the P-value for test of no association
Controls | ||
---|---|---|
ADAMTS-13 | VWF | |
Age* | −0.019 (P = 0.04) | 0.010 (P < 0.0001) |
Systolic BP | 0.0003 (P = 0.94) | 0.0003 (P = 0.76) |
Diastolic BP | 0.006 (P = 0.32) | −0.001 (P = 0.36) |
Total cholesterol | 0.205 (P = 0.0005) | 0.017 (P = 0.28) |
HDL-cholesterol | −0.678 (P < 0.0001) | −0.016 (P = 0.71) |
Triglycerides | 0.021 (P = 0.03) | 0.009 (P = 0.22) |
BMI | 0.077 (P < 0.0001) | 0.004 (P = 0.30) |
Fibrinogen | 0.181 (P = 0.12) | 0.107 (P = 0.0004) |
CRP | 0.005 (P = 0.57) | 0.004 (P = 0.10) |
BMI, body mass index; BP, blood pressure; CRP, C-reactive protein; HDL-cholesterol, high-density lipoprotein-cholesterol.
Adjusted for sex.