Table I.
Percentage of polymorphonuclear neutrophil (PMN) in somatic cell counts (SCC) in the mammary secretions from the mammary glands infused with rbIL-8, placebo saline, or untreated
| PMN (%) (mean ± Sx̄)
|
|||||
|---|---|---|---|---|---|
| Time (h) | Placebo salinea | rbIL-8 (5 μg)a | Placebo salineb | rbIL-8 (25 μg)b | Untreatedc |
| −24 | 38.8 ± 3.0 | 40.2 ± 3.9 | 40.3 ± 2.5 | 38.7 ± 3.6 | 38.5 ± 1.2 |
| 0 | 40.5 ± 3.4 | 39.0 ± 2.8 | 39.5 ± 3.1 | 40.8 ± 4.8 | 38.2 ± 0.9 |
| 10 | 39.7 ± 2.5 | 42.3 ± 1.2 | 40.3 ± 4.2 | 53.0 ± 8.8 | 38.8 ± 1.5 |
| 24 | 38.2 ± 3.3 | 70.0 ± 6.4 | 38.7 ± 3.9 | 90.8 ± 1.4 | 37.7 ± 1.3 |
| 72 | 35.7 ± 2.4 | 73.5 ± 5.5 | 33.8 ± 2.5 | 92.0 ± 1.2 | 34.5 ± 1.4 |
| 168 | 30.3 ± 0.4 | 58.2 ± 5.3 | 30.8 ± 1.9 | 90.5 ± 0.6 | 29.2 ± 2.2 |
| 336 | 26.8 ± 1.3 | 45.8 ± 4.0 | 28.0 ± 1.4 | 87.8 ± 2.2 | 24.8 ± 1.5 |
| 720 | 23.3 ± 2.0 | 34.8 ± 5.2 | 24.0 ± 3.1 | 78.2 ± 4.1 | 21.5 ± 2.9 |
a
rbIL-8 (5 μg in 10 mL of saline) and placebo saline were individually infused into the left- and right-front mammary glands, respectively, of 3 cows following the final milking.
b
rbIL-8 (25 μg in 10 mL of saline) and placebo saline were individually infused into the left- and right-front mammary glands, respectively, of 3 cows following the final milking.
c
No infusion was done in the udders of 3 cows at drying off.