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N15 Cro crystallizes as the biological dimer. The N15 Cro dimer (chains A and B in gold with helix-turn-helix motif highlighted in blue) is shown above the crystal structure of 434 CI repressor complexed with operator DNA (PDB ID 2OR1; protein: wheat with helix-turn-helix motif highlighted in cyan; DNA: gray). Note the approximately equivalent spacing and orientation of the recognition helices in the two dimers. This figure was prepared using PyMOL (DeLano Scientific).
