Table 4.

Comparison of the numbers and types of human progeny present after 6–8 weeks in NOD/SCID recipients of various subsets of fresh or cultured human CB cells expressed per injected CRU

Endpoint	Light-Density	CD34+CD38+	CD34+CD38−	Cultured Cells
CD34−CD19+	0.9  ×  107	0.8  ×  107	1.0  ×  107	0.1  ×  107
CD34+	2.2  ×  106	2.5  ×  106	2.2  ×  106	0.4  ×  106
CD41+	4.0  ×  105	2.0  ×  105	5.0  ×  105	2.0  ×  105
BFU-E	2,800	7,000	3,500	1,300
CFU-GM	27,000	28,000	28,000	9,000
CFU-GEMM	150	130	520	180
LTC-IC	200	1,300	240	50

Values shown are average estimates calculated by dividing the average total number of each type of human progeny measured in recipients in the limiting dilution experiments shown in Table 2 by the total number of CRU that were assayed (based on the CRU frequency values shown in Table 3).