Table 1.

Effect of 1 or 4 weeks overload on muscle mass in wt and LKB1 KO mice

Overload	Bodyweight (g)	CTL (mg)	OVL (mg)	% Difference
1 week
wt	25.4 ± 2.40	17.7 ± 1.28	24.4 ± 1.68*	38.8 ± 7.75
LKB1 KO	26.1 ± 3.56	16.0 ± 0.79	20.3 ± 1.89*	27.8 ± 12.98
4 weeks
wt	27.9 ± 1.08	16 ± 1.17	28.6 ± 4.09*	75.8 ± 15.2
LKB1 KO	26.9 ± 0.49	15.9 ± 1.51	28.7 ± 2.93*	85.0 ± 22.6

Mean body weight and muscle mass from control (CTL) and overloaded (OVL) legs ± s.e.m. Average percentage difference in muscle mass from the CTL and OVL legs of the same animal ± s.e.m.

^*indicates different from control, P < 0.05.