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. Author manuscript; available in PMC: 2009 Jan 15.
Published in final edited form as: Arch Biochem Biophys. 2007 Oct 30;469(2):184–194. doi: 10.1016/j.abb.2007.10.015

Fig. 1.

Fig. 1

Red box: Postulated mechanism for the cyclization of farnesyl diphosphate (FPP) to trichodiene by trichodiene synthase; OPP = diphosphate, NPP = nerolidyl diphosphate [12]. For a proposed mechanistic variation, see the recently reported work of Hong and Tantillo [34]. Proposed mechanisms leading to alternative sesquiterpene products are also indicated.