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Aβ analysis by dot blot. No differences existed between TGSED and TGRUN for total Aβ in the soluble fraction of hippocampal samples, evaluated by 6E10 antibody (A). Aβ fibrils, detected by OC antibody, were significantly decreased in TGRUN animals compared to TGSED (p = 0.01)(B). A representative dot blot is shown (C).
