Table 2.
Total | Not on TMP-SMX at baseline | On TMP-SMX at baseline | Previously received TMP-SMX | |
†Pathogenic organisms | ||||
S. pneumoniae | 48 (26.5%) | 9 (5%) | 36 (19.9%) | 3 (1.7%) |
§Gram negative respiratory organism (M. catarrhalis, H. influenzae) | 48 (26.5%) | 7 (3.2%) | 35 (19.3%) | 6 (3.3) |
S. aureus | 44 (24.3%) | 10 (5.5%) | 31 (17.1%) | 3 (1.7%) |
Enterobacteriacae | 32 (17.7%) | 13 (9.9%) | 18 (9.9%) | 1 (0.5%) |
Non-fermenters including Pseudomonas aeruginosa # | 5 (2.8%) | 4 (2.2%) | 1 (0.5%) | 0 |
Acinetobacter species ¶ | 4 (2.2%) | 3 (1.7%) | 1 (0.5%) | 0 |
† 10 subjects had 2 organisms and 2 had 3 organisms isolated from a NP swab.
§M. catarrhalis n – 22; H. influenzae – n – 26
TMP-SMX exposure: More than 1 organism per subject
Organisms not included – Coagulase negative staphylococcus – 10; Streptococcus viridans – 2; other commensals – 11; no growth – 10; contaminants – 3
# p = 0.0104 (Fisher's Exact 2-tail test)
¶p = 0.048 (Fisher's Exact 2-tail test)