Table 3.

Risk factors for colonization by selected bacteria.

Organism	Odds ratio (95% CI)	Bivariate p-value	Multivariate logistic regression	Wald p-values
Enterobacteriaceae
Age < 1 year	4.6 (2–11.1)	0.0004	4.4 (1.9–10.9)	0.0008
Stage C disease	3.7 (1.6–8.6)	0.002	3.6 (1.5–8.6)	0.005
Female	0.5 (0.23–1.19)	0.13
CDC Immunological Class 2 or 3	2 (0.7–6.9)	0.23
Weight for age-Z-score <-2	1.6 (0.7–3.5)	0.27
No prior TMP-SMX at baseline	0.3 (0.03–1.3)	0.22
Present and/or previous hospitalization	1.1 (0.4–3.7)	0.9
S. aureus	1 (0.3–3.8)	1
Age < 1 year	1.2(0.6–2.4)	0.6
Stage C	0.1 (0.6–2.9)	0.4
Weight for age-Z-score <-2	2 (1–3.9)	0.051	1.7 (0.8–3.5)	0.11
CDC Immunological Class 2 or 3	3.7 (1.4–12.9)	0.007	3.4 (1.3–11.8)	0.029
Female	1.2 (0.63–2.4)	0.54
No prior TMP-SMX at baseline	0.97 (0.42–2.1)	0.94
Present and/or previous hospitalization	2.04 (0.8–6.3)	0.14
S. pneumoniae
Age < 1 year	0.53 (0.2–1.1)	0.09
Stage C	0.51 (0.2–1.6)	0.13
Weight for age-Z-score <-2	0.71 (0.4–1.4)	0.31
CDC Immunological Class 2 or 3	0.8 (0.4–1.6)	0.5
Female	0.97 (0.5–1.9)	0.92
No prior TMP-SMX at baseline	1.4 (0.4–5.3)	0.67
Present and/or previous hospitalization	0.64 (0.29–1.46)	0.28
Gram-negative respiratory organisms
Age < 1 year	0.53 (0.2–0.98)	0.055	0.59 (0.24–1.33)	0.22
Stage C	0.8 (0.3–1.7)	0.51
Weight for age-Z-score <-2	0.46 (0–0.9)	0.029	0.55 (0.25–1.2)	0.14
CDC Immunological Class 2 or 3	0.32 (0.16–0.66)	0.002	0.33 (0.15–0.71)	0.005
Female	1.4 (0.75–2.8)	0.28
No prior TMP-SMX at baseline	5.1 (1.4–22.1)	0.058	0.33 (0.09–0.94)	0.057
Present and/or previous hospitalization	0.5 (0.23–1.12)	0.094	0.63 (0.27–1.54)	0.3

Multivariate logistic regression only where p ≤ 0.1 on univariate analyses

N = 203